Stathmin 1
WebNov 27, 2024 · Stathmin 1 (STMN1) is a microtubule-destabilizing protein highly expressed in hematological malignancies and involved in proliferation and differentiation. Although a … WebApr 12, 2024 · STATHMIN-2 has been shown to be highly expressed in human motor neurons, the cells that primarily degenerate in ALS. ANQUR, a multi-center, randomized, double-blind, placebo-controlled multiple ascending dose study, is the first to assess a therapy that rescues STMN2 expression in patients with ALS.
Stathmin 1
Did you know?
WebHigh-performance liquid chromatography and 2D gel electrophoresis analysis, coupled with mass spectrometry, revealed that stathmin 1 is strongly phosphorylated within only 5 min of exposure to PACAP. Western blot experiments confirmed that PACAP induced a robust phosphorylation of stathmin 1 in a time-dependent manner. On the... More Keywords Web产品名称: Stathmin 2 protein 产品描述: Purified recombinant Human Stathmin 2 protein 反应种属: Human 实验应用: SDS-PAGE 产品浓度: 1 mg/ml 表达系统: E.coli 保存温度: Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles. 运输温度: *Blue Ice* 存储溶液:
WebHigh-performance liquid chromatography and 2D gel electrophoresis analysis, coupled with mass spectrometry, revealed that stathmin 1 is strongly phosphorylated within only 5 min … WebStathmin 1 (STMN1) is a novel cancer biomarker that is also a novel target for treatment in several cancers, including col... View Citations ... 6 Stathmin is overexpressed in a variety of...
http://www.neobioscience.com/prod_view.aspx?TypeId=409&Id=2337947&FId=t3:409:3 WebBackground: Stathmin-1 regulates microtubule dynamics and is associated with malignant phenotypes in non-small cell lung cancer (NSCLC). This study evaluated its diagnostic …
WebSep 20, 2024 · Stathmin-1 has been reported to interact with heat shock protein 27 (HSP27), which is an inhibitor of cyclin-dependent kinases and can promote the proliferation of …
WebGeneral notes. This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved … orbis companyWebStathmin 1 (STMN1), also known as leukemia-associated phosphoprotein p18, metablastin, oncoprotein 18 (op18), phosphoprotein p19, prosolin, protein Pr22, and pp17, is a member … orbis cockpit notaufnahmeWebStathmin 1 (STMN1) is a critical protein involved in microtubule polymerization and is necessary for survival of cancer cells. This editorial describes the role of targeted … orbis computer scienceStathmin is a ubiquitous phosphorylated protein which makes it act as an intracellular relay for diverse regulatory pathways, functioning through a variety of second messengers. Its phosphorylation and gene expression are regulated throughout development [11] and in response to extracellular … See more Stathmin, also known as metablastin and oncoprotein 18 is a protein that in humans is encoded by the STMN1 gene. Stathmin is a highly conserved 17 kDa protein that is crucial for the regulation of the cell See more Stathmin, and the related proteins SCG10 and XB3, contain a N-terminal domain (XB3 contains an additional N-terminal hydrophobic region), … See more Stathmin interacts with two molecules of dimeric α,β-tubulin to form a tight ternary complex called the T2S complex. One mole of stathmin … See more Mice without stathmin have deficiency in innate and learned fear. Stathmin−/− females do not assess threats well, leading to lack of … See more The function of Stathmin is to regulate the cytoskeleton of the cell. The cytoskeleton is made up of long hollow cylinders named microtubules. These microtubules are made up of alpha … See more Stathmin's role in regulation of the cell cycle causes it to be an oncoprotein named oncoprotein 18 (op18). Stathmin (aka op18) can cause … See more • Sobel A (August 1991). "Stathmin: a relay phosphoprotein for multiple signal transduction?". Trends in Biochemical Sciences. 16 (8): 301–5. doi:10.1016/0968-0004(91)90123-D. PMID 1957351. • Steinmetz MO (May 2007). "Structure and … See more orbis clothesWebStathmin 1 (STMN1) is a candidate oncogene whose activity is influenced by p53, p27Kip1 (p27), and PI3K/Akt pathway activation. As a microtubule destabilizing protein, STMN1 … orbis coachingWebOur Stathmin 1 polyclonal, recombinant monoclonal, monoclonal and recombinant polyclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have … ipod bluetooth fm transmitterWebThe E2F transcription factor 1 transactives stathmin 1 in hepatocellular carcinoma Upregulation of E2F1 and STMN1 proteins associate with worse outcomes in patients … ipod bluetooth headphones review