WebNov 6, 2024 · Figure 1: A 64-year-old man with anti-Jo-1-positive antisynthetase syndrome. Hyperkeratosis visible on (A) his right hand, consistent with “mechanic’s hands” and (B) his right foot, consistent with “hiker’s feet.”. The patient required high-flow oxygen and was admitted to the intensive care unit. High-resolution computed tomography ... WebJan 24, 2024 · Common symptoms include inflammation of the muscles (myositis), inflammation of several joints (polyarthritis), interstitial lung disease and thickening and cracking (fissuring) and discoloration of the skin of the fingers, called mechanic’s hands).
Mechanic’s hands and hiker’s feet in antisynthetase syndrome
WebAug 1, 2024 · Mechanic’s hand is a representative manifestation of antisynthetase syndrome (AS) but is observed in other forms of dermatomyositis 1.This is a nonpruritic, hyperkeratotic, and scaly eruption on the ulnar side of the thumb and radial side of other fingers; occasionally the palms, fingertips, and feet are involved. WebApr 1, 2024 · The terms used were mechanic's hands, mechanics hands, dermatomyositis, histopathology, antisynthetase syndrome, and anti-synthetase syndrome in different combinations. The list of references for each relevant article was also examined. A total of 64 citations were found: 34 original studies, 23 case series/reports, and 7 literature reviews. red key property services newport
Dermatomyositis - Diagnosis and treatment - Mayo Clinic
WebMyositis. Myositis is a rare disease in which the immune system chronically inflames the body's own healthy muscle tissue. Over time, this persistent inflammation weakens muscles, often resulting in muscle aches, pain, and fatigue. There are several types of myositis. It usually develops slowly over time with symptoms that range in severity ... WebJun 25, 2024 · Mechanic’s hand is described as fissuring and cracking of the skin of the palms, predominantly involving the distal and lateral part of the phalanges and the ulnar aspect of the thumbs. It is a specific sign of antisynthetase syndrome, seen in 20–70% cases [ 1 ]. Differential diagnoses include eczema, psoriasis and irritant contact dermatitis. WebMechanic's Hands is a descriptive term for the changes in the hands of patients with dermatomyositis and polymyositis. Mechanic’s hand is usually more associated with anti-synthetase autoantibodies, including the myositis-specific anti-Jo1 autoantibodies. Like most forms of Myositis, it is considered a chronic autoimmune disease prima… Join our Clubhouse Club, Myositis Support, for weekly support rooms, and for po… richard blum fact check