Cytostatically
WebFeb 1, 2003 · The first series of synthetic 1-aza-9-oxafluorenes with cytostatic activities in the micromolar range was evaluated as cyclin-dependent kinase (CDK1) inhibitors. Activity was found to be selective in comparison to the inhibition of other kinases within the CDK family. Compounds were shown to inhibit the membrane-efflux pump P-glycoprotein … WebJul 8, 1997 · Most of the cytostatically active phospholipids synthesised have been structural analogues of lysophosphatidylcholine. In recent years a series ofglycerophospbolipid ethers with modified head groups were also found to exhibit cytostatic properties2. Synthetic serine phospholipids appeared to be of special interest in view of …
Cytostatically
Did you know?
WebAug 1, 1980 · Sodium azide acted cytostatically to cytotoxically on 2 lines of mammalian cells. After application of the substance in an acid environment the highest cytostatic effect was noted. WebThe initial metabolism of the oxazaphosphorine cytostatic ifosfamide (IF) consists of two different pathways: ring oxidation at carbon-4 forms the cytostatically active metabolite 4-hydroxyifosfamide (4-OH-IF, “activated ifosfamide”), whereas side-chain oxidation with liberation of the presumably neurotoxic compound chloroacetaldehyde (CAA) that …
Webcy·to·plasm. (sī′tə-plăz′əm) n. The protoplasm enclosed by the plasma membrane of cell, excluding the nucleus in eukaryotic cells and cellular DNA in prokaryotic cells. cy′to·plas′mic (-plăz′mĭk) adj. cy′to·plas′mi·cal·ly adv. American Heritage® Dictionary of the English Language, Fifth Edition. WebCombined CDK4/6 and mTOR inhibition cytostatically inhibit proliferation and trigger G0–G1 cell cycle arrest. Having observed that the combination of palbociclib and temsirolimus potentiated each drug’s cytostatic effects, we next investigated whether these effects continued beyond the initial 24-hour period. Low, sublethal doses of each ...
WebNCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. WebFeb 23, 2024 · Cytostatically active antimetabolites Other asparaginase, hydroxyurea, radium-223-dichloride Classification according to substance groups and substances: Antimetabolites Folic acid analogues Methotrexate Pemetrexed Purine analogues 6-mercaptopurine Pentostatin Cladribine Pyrimidine analogues 5-fluorouracil Capecitabine …
WebChemotherapy remains the mainstay means for treatment of malignancies either by cytotoxicity or cytostasis.DNA damage and subsequent induction of apoptosis is the primary mechanism of cytotoxic drugs like antimetabolites …
WebCytostatically Definizione: in a cytostatic manner Significato, pronuncia, traduzioni ed esempi csv to binaryCytostasis (cyto – cell; stasis – stoppage) is the inhibition of cell growth and multiplication. Cytostatic refers to a cellular component or medicine that inhibits cell division. Cytostasis is an important prerequisite for structured multicellular organisms. Without regulation of cell growth and division only unorganized heaps of cells would be possible. Chemotherapy of cancer, treatment of skin diseases and treatment of infections are common use c… earned income limits for earned income creditWebcytostatic (redirected from cytostatically) Also found in: Dictionary, Medical. Related to cytostatically: cytolytic, Keratolytic, cytocidal cytostatic [ ‚sīd·ō ′stad·ik] (cell and … csv to base64Webcytostatic adjective Referring to that which suppresses cell growth and multiplication noun An agent that suppresses cell growth and multiplication McGraw-Hill Concise Dictionary … earned income relief irascsv to autocad software free downloadWebA series of cytostatically active metabolites have been isolated from microorganisms in recent years. These compounds, which are chemically closely related, are of a new structural type. A highly substituted hydrogenated isoindolone unit is fused to an 11- to 14-membered macrocycle. The large ring may be carbocyclic or heterocyclic (lactone or ... earned income minor roth iraWebHere is the list of all the English words not containing letters B, E, G, J, M, N, P and R grouped by number of letters: cytostatically, fatalistically, Hashitoxicosis, holococcoliths, hootchy-kootchy. earned income more than half of support